The St. James's Gate company said the product recall - which only occurs in the UK - was due to concerns about microbiological contamination and only affected the new Guinness 0.0 drink.
Guinness said in a statement that "some cans may not be safe to consume" and urged people not to drink them but to return them instead for a full refund.
Guinness 0.0 was launched in the UK only three weeks ago. It will be on sale in Ireland in the next few days.